Publications

Fatima Rabab et al. Hepatitis C Virus Care Continuum: Integrating Point-of-Care RNA Assay and Direct-Acting Antivirals.

Since its discovery in 1989, the hepatitis C virus (HCV), a hepatotropic RNA virus, has emerged as a global health threat with an estimated 71 million individuals infected worldwide, the vast majority of whom remain oblivious to their condition. This bloodborne virus exhibits profound genetic heterogeneity, spanning seven major genotypes and numerous subtypes. HCV primarily […]

21 January 2025

Bouamar et al. Comparison of Two Field Deployable PCR Platforms for SARS-CoV-2 and Influenza A and B Viruses Detection

Background: Respiratory viral infections are a major public health challenge and the most diagnosed medical condition, particularly for individuals living in close proximity, like military personnel. We compared the sensitivity and specificity of the Biomeme FranklinTM and Truelab® RT-PCR thermocyclers to determine which platform is more sensitive and specific at detecting SARS-CoV-2 and influenza A […]

30 December 2024

Panta et al. Community Screening for High-Risk Human Papillomavirus Infection Using Self-Sampling and Point-of-Care Test

Objective: HR-HPV types 16 and 18 are responsible for pre-invasive and invasive lesions of the cervix, accounting for 70-80% of the total subtypes. The aim of this study was to investigate the prevalence of high-risk HPV subtypes 16 and 18 in self-collected vaginal samples using real-time micro-PCR and to study the acceptability of self-sampling.Methods: Eligible […]

02 November 2024

Reddy et al. Hepatitis C Virus Seroprevalence and Genotypic Diversity Among Haemodialysis Patients in a District Hospital- A Study in Telangana

Background: Hepatitis C virus (HCV) infection poses a significant threat to public health globally, particularly among patients undergoing haemodialysis. The prevalence and genotypic diversity of HCV in this population warrants investigation to guide targeted interventions. Objectives: This prospective study aimed to assess the prevalence of HCV infection and characterize the distribution of HCV genotypes among […]

16 September 2024

Jasrotia et al. Assessing knowledge and awareness levels regarding cervical cancer and HPV vaccination in the Jammu regions

Background and Objectives: Cervical cancer global burden is highly skewed towards poor countries primarily due to lack of awareness, poor screening, and low uptake of prophylactic vaccines. The purpose of our study is to educate and raise awareness among young girls and women about the importance of cervical screening and HPV vaccination. Materials and Methods: […]

17 July 2024

Madhu et al. Evaluation of High-Risk Human Papillomavirus Serotypes as a Primary Screening Tool for Cervical Cancer in a Tertiary Care Center

Cervical cancer represents a critical public health challenge, especially in developing countries where it significantly contributes to cancer-related mortality among women. Human papillomavirus (HPV) infection is a primary etiological factor for cervical cancer. In India, cervical cancer accounts for 9.4% of all cancers and 18.3% of new cancer cases. Despite the availability of cytological screening […]

15 July 2024

Sharma et al. Current status of diagnostic assays for emerging zoonotic viruses- Nipah and Hendra

Introduction: Nipahand Hendra viruses belong to the Paramyxoviridae family, which pose a significantthreat to human health, with sporadic outbreaks causing severe morbidity andmortality. Early symptoms include fever, cough, sore throat, and headache,which offer little in terms of differential diagnosis. There are no specifictherapeutics and vaccines for these viruses. Areas covered: Thisreview comprehensively covers a spectrum […]

12 June 2024

Prakash et al. The development evaluation performance and validation of micro‑PCR and extractor for the quantifcation of HIV‑1‑2 RNA

HIV infection has been a global public health threat and overall reported ~ 40 million deaths. Acquired immunodeficiency syndrome (AIDS) is attributed to the retroviruses (HIV-1/2), disseminated through various body fluids. The temporal progression of AIDS is in context to the rate of HIV-1 infection, which is twice as protracted in HIV‑2 transmission. Q‑PCR is […]

15 April 2024

Rajkumar et al. Decentralised same day testing of HCV levering existing peer support networks among men who inject drugs- feasibility and efectiveness

Background Prevalence of hepatitis C virus (HCV) infection among people who inject drugs in the state of Manipur, India, is 43%; however, access to care is poor. We piloted a Community-led and comprehensive hepatitis care model that included same-day HCV treatment at drug treatment centres. Methods Screening was conducted through venipuncture samples collected by community […]

06 April 2024

Singh et al. Chip-Based Real-Time RT-PCR (TrueNat) Versus Conventional Real-Time RT-PCR for Swift Diagnosis of SARS-CoV-2

The emergence of SARS-CoV-2, a novel coronavirus, has resulted in a global pandemic with rapid spread and significant public health implications. Diagnostic testing plays a pivotal role in identifying and managing COVID-19 cases. This study describes a chip-based real-time reverse transcriptase polymerase chain reaction (RT-PCR) method, TrueNat, for diagnosing SARS-CoV-2. The protocol involves RNA extraction […]

01 March 2024

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