Introduction: In December 2019, Wuhan, a province in China, reported an outbreak of pneumonia which was said to be due to a novel strain of Coronavirus. Initially, it was named as 2019-nCoV by WHO and later as SARS CoV -2. Early and accurate detection of SARS CoV 2 is necessary for isolating and treating the infected individuals. WHO has recommended molecular methods as the method of choice for detection of SARS CoV 2 viral infection. Recently, ICMR, the apex body for medical research and validation of methods, recommended an indigenous Truenat RTPCR (Molbio diagnostics)system for screening of SARS CoV2 infection to NABL accredited private laboratories.